Over several decades, mental health clinic research has shown that ketamine has antidepressive prope
Over several decades, mental health clinic research has shown that ketamine has antidepressive properties. Ketamine is approved by the U.S. Food and Drug Administration as an anesthetic, although it is also being used for the management of psychiatric disorders and chronic pain management. Ketamine has been incorporated into the treatment of psychiatric disorders, such as major depressive disorder, bipolar disorder, and post-traumatic stress disorder , as well as post-operative and chronic pain management. Ketamine infusion therapy for psychiatric disorders or chronic pain management and may be considered by the patient’s interdisciplinary team after standard treatment.
Ketamine infusion therapy involves the administration of a single infusion or a series of infusions for the management of psychiatric disorders like major depressive disorder, post-traumatic stress disorder, acute suicidality.
It’s not entirely clear how ketamine works. Because it exerts an antidepressant effect through a new mechanism, ketamine may be able to help people successfully manage depression when other treatments have not worked.
Ketamine also may influence depression in other ways. For example, it might reduce signals involved in inflammation, which has been linked to mood disorders, or facilitate communication within specific areas in the brain. Most likely, ketamine depression treatment works in several ways at the same time, many of which are being studied.
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